[2] Its building, constructed in 1900, is an important local example of Romanesque architecture, and was listed on the National Register of Historic Places in 1979.

[1] St. Anne's stands north of Berlin's central business district at the northeast corner of Pleasant and Church streets.

It is a roughly rectangular red brick structure, with a long gabled roof and towers flanking the south-facing front facade.

[4] It was built by M. H. Roy, a contractor from Lewiston, Maine; the identities of the artisans who created its interior are not known.

By the 1970s Berlin's Roman Catholic congregations had grown to four, with St. Anne's principally serving its French-American population.