It is noted for its sports teams and exceptional grades that are usually at or above the provincial expectations.

The motto of St. Anne's is "in alis aquilae"[2] which is Latin for "on eagle's wings".

When the school opened, only 139 students were enrolled, but from a wide catchment across Huron County, including Clinton, Goderich, Bayfield, Wingham and Blyth.

[3] St. Anne's is a rural school and as such, it fills a unique need of catering to those who wish to enter agriculture.

The families are generally members of the Roman Catholic Church in the Dioceses of London.

The track and field teams are also very popular and have had multiple people go to OFSAA nearly every year.