Dedicated to St. Anthony of Padua, it is the episcopal seat of the Catholic diocese of Patos de Minas.

[3] The Parish of Santo Antonio was established in Patos de Minas on May 31, 1850, through Provincial Law 472.

In the place where today the Memorial of Patos de Minas, there was a chapel that was built in 1839.

The idea of constructing a new parochial church appeared in 1892 and a committee for this purpose was established in 1917 by Canon Getulio Alves de Melo.

Since the creation of the Catholic diocese of Patos de Minas, on April 5, 1955, the parish became a cathedral, which was solemnly consecrated on October 28, 1961 by the then archbishop of Brasilia, the priest José Newton de Almeida.