Benilde underwent through the supervision of University of St. La Salle and the De La Salle Brothers, and is now a member of Association of Lasallian Affiliated Schools (ALAS), a network of Lasallian private schools.

The school serves the community of students from neighboring subdivisions such as Lasalleville, St. Benilde Homes, Grandville, Hillside, Forest Hills, and Regent Pearl.

Rolando Dizon FSC, a past President of De La Salle University, Manila, in 1987.

The athletics program includes varsity football, basketball, volleyball, table tennis, and chess.

School organizations includes the Student Affairs Council (SAC), Campus Peer Ministry (CPM), CPM Choir, and St. Benilde CHIMES: The official school publication of St. Benilde.