St. Clair High School is a high school in St. Clair, Missouri, United States, and is part of the St. Clair R-XIII School District in Franklin County, Missouri.

Saint Clair's mascot is "Spike" the bulldog.

Three students, a freshman, a sophomore and a junior committed suicide during a period of seven weeks[2] in 2012.

[4] In 2023, St. Clair High School made national news[5][6] after two teachers[7][8] were forced to resign after they were discovered producing and appearing in pornographic videos on OnlyFans.

One of the teachers, whose annual salary was $42,000 before she resigned, had made nearly $1 million producing content on OnlyFans.