St. Francis Xavier College (Colégio São Francisco Xavier) is a Brazilian co-educational Catholic school located in the Subprefecture of Ipiranga of the city of São Paulo.

Guido del Toro arrived in Brazil from Italy in 1914 and dedicated himself to the evangelization of Japanese immigrants.

In 1928, he founded Japanese Catholic College of St. Francis Xavier in a rented house on Liberty Street.

He received the present property in 1929 and by 1931 resituated the school there, still dedicated to serving the Japanese.

With the completion of a new building in 1966, it became a high school and took the name St. Francis Xavier College.