[8] The school is named after Ralph C. Wilson, Jr., the founding owner of the Buffalo Bills professional football team.

It awards a Doctor of Pharmacy degree to candidates who successfully complete four years of professional study.

Need-based and merit-based scholarships, as well as grants, loans, and part-time employment, are available for eligible students.

[10] Growney Stadium is home to Fisher's football, field hockey, soccer, and lacrosse teams.

The Manning & Napier Varsity Gymnasium is home to the men's and women's basketball teams.

In 2006, Fisher's football team finished the season with a 12–2 record overall and shared the Empire 8 Conference title.

In 2006, Fisher advanced to the Elite Eight of the NCAA Men's Division III Basketball Championship Tournament.

Under Kahler, the women's basketball program reached the NCAA Division III Championship Tournament 14 times and played in the NCAA Women's Division III Basketball Championship game in 1988 and 1990.

The women's basketball team is now led by Melissa Kuberka who was hired as a head coach before the 2017-18 season.

Since 2000, St. John Fisher University has been home to the Buffalo Bills' NFL summer training camp.

[15][16] This project funds a trip to Florida for the children of Camp Good Days and has raised over $1.8 million since its inception.