It is the seat of Archbishop John Baptist Odama, head of the Roman Catholic Archdiocese of Gulu.

[1] Construction of the 5 000-seat cathedral, organized by the Comboni Missionary Brothers, was a massive effort.

Brother Attilio Consolaro supervised the work from the beginning to the end, and in honor of this achievement, a street in Rome was named after him.

The remains of Bishops Angelo Negri and Cipriano Kihangire were laid to rest in this cathedral.

On 6 February 1993, Pope John Paul II entered the cathedral to adore the Holy Eucharist as thousands of people turned up to see him.