The system includes a 194-bed teaching hospital, a 200-bed nursing home, two affordable senior housing facilities for frail elderly residents, a family medicine residency program, a podiatric surgery residency program, state-of-the-art technology, a 138-bed psychiatric hospital (St. Vincent's Hospital Westchester in Harrison) and satellite clinics in Yonkers, White Plains, Port Chester, Brooklyn, Queens and Staten Island.

It was founded in 1888 as St. Joseph's Hospital by the Sisters of Charity of New York.

The HealthGrades website contains the latest quality data for St. Joseph Medical Center (of Yonkers), as of 2015.

For this rating section three different types of data from HealthGrades are presented: quality ratings for seventeen inpatient conditions and procedures, thirteen patient safety indicators, percentage of patients giving the hospital a 9 or 10 (the two highest possible ratings).

For this hospital the data for this category is: For patient safety indicators, there are the same three possible ratings.