[citation needed] The church occupies the probable second site of the Missión San Antonio de Valero (later known as the Alamo), before it was moved in 1724 to its present location.

[8] In the 1870s, Friar Henry Pfefferkorn, founder of the Liederkranz (male singing choir), painted the Annunciation and Assumption murals on the side altars.

[11] In 1944, Joske's department store (whose site would eventually become part of the Shops at Rivercenter complex) offered to buy the church grounds in order to develop it commercially.

[12] Today, the parish serves as home to a multicultural community and as a popular attraction for tourists.

[12] Spanish-language masses are held with mariachi music[4] and the San Antonio Liederkranz sings once a month.