During World War II, the plant produced the DUKW amphibious vehicles for the military.

During the 1981 model year, Corvette production ended and shifted to Bowling Green Assembly Plant in Kentucky [3] Thereafter, the factory only manufactured R- and V-series crew cab and cab/chassis trucks before that output was moved to GM's Janesville Assembly.

[4] Automobile production and maintenance workers were transferred from the closed truck line to the new Wentzville Assembly in 1986 which produced Buick and Oldsmobile front wheel drive replacements for the old rear wheel drive B Body cars.

[1] The plant closed on August 7, 1986, its future essentially sealed when GM closed the Caprice/Impala assembly on August 1, 1980 and began developing a new factory, Wentzville Assembly — a then-state of the art, 3.7 million square foot plant on 569 acres approximately 40 miles (64 km) west of St. Louis, just off of I-70.

As of 2022, the Union Seventy Center, a 161-acre industrial warehouse stands where the former factory operated.