St. Luke's emergency department treats over 55,000 patients each year and the most cases of trauma in Iowa.

This has led to a partnership with the University of Iowa Hospitals and Clinics for training future ER doctors.

It is the area's only Level III Regional Neonatal Intensive Care Unit.

[1] In 1881 a critically injured homeless man who was unable to get care in Cedar Rapids inspired a local Episcopal minister to act.

St. Luke's Hospital was one of the buildings in Downtown Cedar Rapids that didn't sustain any damage from the Iowa Flood of 2008.