It is the only church in Iowa designed by nationally prominent architects Cram & Ferguson, who specialized in ecclesiastical architecture.

The St. Luke's church was eventually provided to the Monticello Heritage and Cultural Center, a group interested in its preservation, which obtained a grant from the Historic Site Preservation Grant Program of the State Historical Society of Iowa in 2000, enabling it to purchase the property.

[2]: 8, 17 There was a design challenge in the small church's requirement for a large community room, as a steeply pitched roof consistent with Late Gothic Revival styling could have required a very high roofline, higher than on the main church area.

Gothic Revival styling is also apparent in building materials choices and in many architectural details.

[1] It was deemed significant as an illustration of how the Cram & Ferguson architects adapted Late Gothic Revival styling to the design of a small church.