Saint Martinville Senior High School (SMSH, also known locally as Senior High) is a high school in St. Martinville, Louisiana, United States.

St. Martinville Senior High School is a 9th–12th Grade public school in St. Martinville, Louisiana.

Enrollment in 2016–2017 is estimated to be around 750 students.

It is located at 762 N Main St - St.Martinville, LA 70582.

St. Martinville Senior High athletics competes in the LHSAA.