The airport is also located 8 nmi (15 km) west of Naval Air Station Patuxent River.

St. Mary's County Regional Airport covers an area of 200 acres (81 ha) which contains one asphalt paved runway (11/29) measuring 4,150 x 75 ft (1,265 x 23 m).

[1] For the 12-month period ending March 14, 2023, the airport had 40,308 aircraft operations, an average of 110 per day: 97% general aviation, 3% air taxi and <1% military.

There was 207 aircraft based at this airport: 171 single engine, 19 multi-engine, 4 jet, 5 helicopters, 1 ultralight and 7 gliders.

The St. Mary's Composite Squadron (MER-MD-089)[5] of the Civil Air Patrol[6] meets at the terminal building and bases their aircraft there as well.