St. Mary Catholic Secondary School is a Catholic secondary school located in Hamilton.

It is a part of the Hamilton Wentworth Catholic District School Board.

Due to overcrowding, planning for a new school on the current location started in 1992.

[1] St. Mary Catholic Secondary School feeder schools are: Canadian Martyrs, Guardian Angels, and St. Joseph in Hamilton; Our Lady of Mount Carmel in Carlisle; St. Augustine and St. Bernadette in Dundas; and St. Thomas in Waterdown.

[3] The woman’s program has captured 12 National Championship titles, while the men’s program earned its first national championship title in 2005.