St. Nicholas of Tolentine High School was a four-year, coeducational Catholic high school located in the University Heights neighborhood of the Bronx, New York.

[2] A parochial school operated by the parish of the same name, St. Nicholas of Tolentine Church, it opened in 1927 and closed in 1991, after years of declining enrollment.

[2] The final class of 68 students graduated on June 14, 1991.

[4] In 1975, Tolentine had the city's top-ranked high school basketball team.

[5] It won the Catholic High School Athletic Association basketball championship in 1980–1982 and 1988.