Founded in 1832, the parish has occupied several different buildings as the population of English-speaking Catholics, primarily Irish, in Quebec City grew or declined.

English-speaking Catholics in the city were organized into a separate congregation with a dedicated priest in 1822.

Helene, on what is now McMahon Street (named after Father Patrick) inside the walls of the Old Quebec.

Designed by Thomas Baillarge it opened for worship on July 7, 1833,[3] It was at first a chapel of Notre-Dame with sacramental registers kept at the cathedral.

It burned in 1970 and its outside facade was reused as part of an annex of the Hôtel-Dieu de Québec hospital.