The seminary is affiliated with the University of Ghana in Legon, Greater Accra Region.

The aim was to separate the philosophy department of St. Peter's Regional Seminary, Pedu, Cape Coast, from that of Theology.

There was also the need to initiate a spiritual year programme in response to the promptings of Pope John Paul II.

The idea came to fruition when on January 15, 1988, the first batch of seminarians (48 young men) arrived to start the Spiritual Year Programme.

Stephen Acheampong, John Martin Darko, and Miachael Barima Apau joined the staff.

Irvin Yangouru and Joseph Osei Bonsu also joined the staff from the University of Ghana.