It presently offers academic programs in basic education, tertiary and post-graduate studies in the fields of Information Technology, Teacher Education, Business, Accountancy, Liberal Studies, Nursing, Tourism, Hospitality, Psychology, Sciences, Physical Therapy, and many others.

At present, though SPUI is part of the St. Paul University System, it remains distinctively independent with its own administration.

Initially opened with 70 students, the school quickly grew, achieving government recognition for its 3-year diploma program in 1948.

The Social Laboratory Extension Program (SLEP) was also established during this period, fostering community outreach initiatives.

New programs, including Bachelor of Secondary Education and Associate in Hotel and Restaurant Management, were introduced.