The Eparchy is not part of any ecclesiastical province, but is immediately subject to the Holy See and depends on the Dicastery for the Oriental Churches.

Bishop of Rajkot Gregory Karotemprel, the chair of the Commission for the pastoral care for the migrants and apostolic visitator to USA and Canada, made an extensive study of the pastoral concerns of the Syro-Malabar immigrants in the United States and Canada by visiting the major cities in 1996.

He recommended to the Holy See to establish Syro-Malabar diocese for the faithful living in the United States and Canada.

Varkey Vithayathil made a follow-up study in 1998 by visiting major cities in the United States and Canada.

[1] Jacob Angadiath was the director of Mar Thoma Sleeha Mission in Chicago when he was selected as the bishop.

Previously he was the vicar of St. Thomas the Apostle Catholic Church in Garland, TX that he had established in 1992.

[2] The inauguration of the diocese and the episcopal ordination of Jacob Angadiath was held in Chicago on 1 July 2001 at Hyatt Regency Hotel during the Second Syro-Malabar Convention.

Post-Second Vatican Council, the liturgy was translated to Indian languages Malayalam, Hindi, and Tamil as the Syro-Malabar Church was mainly based in India.

Bishop Jacob Angadiath commissioned on behalf of the Synod of the Syro-Malabar Church, Joseph J. Palackal and George Thaila to set the English language Qurbana text to music in 2007.

[6] On May 5, 2018, Kevin Mundackal of Thornwood, New York, was ordained as the first ever American-born Syro-Malabar priest at St. Thomas Syro Malabar Forane Catholic Church, Somerset, NJ.

[7] As of 2023, There are 7 American born priests and 8 Seminarians [8] After the accession of Mar Joy to seat of the Eparch of the Eparchy, In October 2022, He elevated Thomas Mulavanal, the Director of the Knanaya Region as the protosyncellus and Cathedral Rector Thomas Mulavanal as the syncellus.

The Diocesan Curia is a group of people who assist the Eparch in governing the Syro Malabar Eparchy of St. Thomas of Chicago.

Thomas was ordained in 1990 and serves also as the Pastor of Sacred Heart Knanaya Catholic Church Chicago.

Prior to that, He served as the Pastor of St.Mary's, Chicago and St. Pius X Knanaya, Los Angeles Syncellus: Fr.

Prior to that, He served as the Pastor of Our Lady of Good Health, Coral Springs and St Thomas, Somerset.

Danavelil was ordained in 1998 and serves also as the Pastor of St. Thomas Syro-Malabar Forane Catholic Church, Philadelphia and the Eparchial Catechesis Director.

Prior to becoming the Diocesan Procurator, He served as Pastor of St. Joseph Syro Malabar Forane Catholic Church, Houston, St. Mary's (Pearland) and St. Thomas (Bay Area).