The church is constructed in rock-faced gritstone and has a red tile roof.
The Sunday school is attached to the north end of the church.
The church has a five-bay nave with open timber roof and wooden panelling.
The east window depicts the parable of the Good Samaritan and is dated 1907.
St Andrew's Roundhay has a partnership with the Lutherkirche in Frankenthal, Rhineland-Palatinate and the Martinskirche in Bernburg, Saxony-Anhalt, Germany.