The School was established in 1850 by St Andrew's Church to accommodate local children living in the 40 houses that made up Walkerville.

The original School House is still used today as part of the new Gymnasium and Performing Arts Centre.

St Andrew's School caters for approximately 400 students[1] from the Early Learning Centre (ELC) to Year 6 with a strong Music Programme and a wide range of Co-curricular electives including Art, Drama, Tennis Coaching, Gymnastics, Megatronics, Chess and Debating.

St Andrew's is consistently a top performing primary school in South Australia.

In 2018 its year 5 performance was ranked as the number 1 co-ed school based on National Assessment Program – Literacy and Numeracy (NAPLAN) results[2] In 2018 its year 7 NAPLAN performance was ranked first out of the over 125 primary schools in Adelaide with a score of 606, 5 points higher than second place at 601.