St John's Hospital was a mental health facility at Stone, Buckinghamshire, England.

The hospital, which was designed by Thomas Henry Wyatt and David Brandon using a corridor layout, opened as the Buckinghamshire County Asylum in January 1853.

[1] Additional wings to the main building and a detached chapel were added in the late 19th century.

[1] After the introduction of Care in the Community in the early 1980s, the hospital went into a period of decline and closed in 1991.

[1] Despite extensive local protests, the hospital buildings were subsequently demolished and the site redeveloped for residential use.