The church building uses uncoursed limestone rubble with ashlar dressings and was originally constructed in the early Norman period (c.

On the floor of the chancel is the historically important tombstone of the parents of Dr. Thomas Willis FRS, a famous resident of North Hinksey.

[6] His fame arises from his recognition as a pioneer in anatomy and pathophysiology due to his original multidisciplinary work in a clinical setting.

[8][9] The inscription on the tomb reads, in part, Underneath lye Interred THOMAS WILLIS Gent.

[10][11]The tombstone establishes the otherwise uncertain date of the death of Dr Thomas Willis' father, which was a significant event in his early career.

[13] The north wall of the nave is largely the original 12th century construction, being very deep with small window openings.

The doorway and staircase to the former rood loft (a reminder that the church was formally a Roman Catholic one) was reopened in 1913.

A door in south wall dates from the 12th century, and has a Norman beaker clasp carving which is reported in the Corpus of Romanesque Sculpture in Britain and Ireland.

The inscriptions on the bells reads: Winifred Toynbee was a local councillor and social worker.

Chancel north wall - Made in 1890 by Hardman & Co.[15] This was given by Mrs Jane Low of Dundee in memory of her son Alexander, who died age 19 and may have been a student at Oxford University.

Nave south wall - Made in 1881 by Hardman & Co.[15] This depicts the baptised Christ, with a dove bringing the Holy Spirit.

Nave, north wall - Small window made of 15th century glass recovered from the Western Front, 1920.

[15] The south wall of the nave also has a small clear window at a height that allows people from outside to view the church service.