The school's history began in 1915 when Bishop Joseph Shiel proposed a Branch House for the Sisters of the Presentation of the Blessed Virgin Mary be established at Yeppoon.

[5] Mother Ursula Kennedy and Mother Patrick Madden, two Presentation Sisters, visited Yeppoon and selected a one-acre block in Queen Street for the construction of the branch house, which at the suggestion of Bishop Shiel became known as St Ursula's.

[5] With a demand for specialised education for young woman becoming apparent,[5] St Ursula's College was officially opened at the site on 12 March 1918,[8] with an enrolment of 32 students.

[5] The Queensland Presentation Congregation transferred governance of St Ursula's College to Mercy Partners in June 2014.

[9] The plans included the construction of a new two-storey education block with new amenities, courtyard and covered area which would replace an existing building which would be demolished.