[1] The community was named for Edward Stafford, who settled in the area in the late 19th century.

Stafford was alerted to the presence of a mineral spring in the area by Choctaws, who took their wounded and sick there for its purported healing powers.

A bottling works was founded the next year and the spring water was soon shipped throughout the country.

The shareholders sold the company in 1918, and visitors stopped arriving to the springs during the Great Depression.

This Jasper County, Mississippi state location article is a stub.