Stanislav Mikheyev graduated from Faculty of Physics of Moscow State University in 1965.
He worked on Baksan Underground Scintillator Telescope for a long time.
He has been the leader of two experiments carried out on Baksan Telescope: observation of upward-going muons and searches for superheavy magnetic monopoles.
In 1985 Stanislav Mikheyev and Alexei Smirnov considered the propagation of oscillating neutrinos in matter with varying density and suggested an explanation for the solar neutrino problem (the MSW effect).
Mikheyev was awarded the Bruno Pontecorvo Prize (2006, jointly with Smirnov and Wolfenstein) and the Sakurai Prize (2008, jointly with Smirnov).