TX 183 begins in south Fort Worth, near Hulen Mall, heading to the northwest as a freeway from an interchange with I-20 and the Chisholm Trail Parkway.

The route meets with US 377 in a large roundabout, shortly before heading north as Alta Mere Drive into an intersection with Camp Bowie West Boulevard (Spur 580).

TX 183 meets I-30 in a cloverleaf interchange near Ridgmar Mall, turns northeast, and follows along the eastern boundaries of Fort Worth Naval Air Base and White Settlement as Westworth Boulevard.

TX 183 continues east as NE 28th Street, passing north of the Fort Worth Stockyards and running over the interchange with I-35W, after which it forms the northern boundaries of Mount Olivet Cemetery.

The route connects with the southern end of International Parkway, which proceeds north into DFW Airport as TX 183 continues eastward.

TX 183 then enters the former site of the Texas Stadium, proceeding into an interchange with Walton Walker Boulevard (Loop 12) and its toll road.