State Road 61 (SR 61) is located in the Big Bend area of Florida, running through the state capital of Florida, Tallahassee.

The route's southern terminus is at US 98, and its northern terminus is at the Georgia state line, where it continues north as Georgia State Route 35.

SR 61 begins at US 98 as an unsigned route, heading north on US 319, until it splits off with the highway in Crawfordville and becomes County Road 61.

[citation needed] The main, signed portion of SR 61 begins at the Leon County line, where it continues north and eventually rejoins US 319 just south of Capital Circle.

The swapping ends at Paul Russell Road and then joins with US 27 as Monroe Street.