[3][4] It is endemic to Guyana where it is known from Mount Ayanganna (the type locality) and Mount Wokomung,[5] both in the Pacaraima Mountains.

[3] Stefania ayangannae are yellowish-brown or yellowish-red frogs with diagonal paravertebral dark brown marks, often joined to form chevrons in their dorsum.

The head has a dark brown patch is present.

Females carry the eggs on their back until they are fully developed and hatch as small froglets; the male and female cooperate to get the eggs on the female's back.

These frogs can be found at night on leaves or branches 1–5 m above ground.