He considers the key to understanding this can be found in some cells (gametes and bacteria), corals, sponges, and in the behavior of organisms such as placozoa.

[13] Other biologists four years prior claimed that trees in conditions of acute water shortage can emit sounds which can be more than just passive signs of cavitation.

Mancuso and his colleagues showed that in the laboratory arabidopsis the root apices are very sensitive to light (a few seconds of illumination are enough to cause an immediate and strong reaction of the molecules of the ROS).

Plants, partly due to symbiosis with bacteria and fungi, "invented" well-optimized and stable methods of colonizing the earth's surface and then the lower atmosphere.

Plants also created one of the most important carbon sinks on our planet, and launched the production of clean energy from starch, sucrose, sclerenchyma and complex biomolecules through photosynthetic chlorophyll, biodegradability according to the principles of a circular economy.

In 2005, Mancuso, together with several biochemists, developed a "non-invasive" microelectrode based on carbon nanotube technology for measuring and fixing the flow of information that can circulate in plants.

Chemicals synthesized by plants often have a very complex effect on the behavior of animals and insects (an example is the mutually beneficial relationship of myrmecophytes and ants, in particular the phenomenon of the devil's garden in Amazonian forests).

[33] In 2012, in the Plantoid project, he took part in the creation of a "bio-inspired" robot that imitated certain natural properties of the roots, and could, for example, explore an area that is difficult to access or contaminated as a result of a nuclear accident or the use of bacteriological weapons.

[36] In 2014, at the University of Florence, Mancuso created a startup specializing in plant biomimetics and an autonomous floating greenhouse,[37] which was offered for mass production to the Chilean government in 2016.