[2] She also played Sam Tyler's future girlfriend in the original pilot of the American television show Life on Mars.

In 2008, she was cast on the Fox series Terminator: The Sarah Connor Chronicles,[3] playing Jesse, a Resistance fighter and girlfriend of Derek Reese.

In April 2009, Jacobsen was cast on The CW's revamped Melrose Place[4] in the role of medical student Lauren Yung.

In 2011, Jacobsen made a cameo appearance in the Two and a Half Men episode "People Who Love Peepholes" as Charlie's former girl friend, Penelope.

In 2012, she appeared in the 2012 detective thriller film Alex Cross (as played by Tyler Perry), as the businesswoman Fan Yau Lee, who becomes the first victim of the antagonist Picasso (Matthew Fox).