Stephen Jacob Chanock (born April 15, 1956) is an American physician and geneticist.
He has held multiple positions, both in research and scientific leadership over his career at the NCI.
[1] He has received numerous awards for his work in the discovery and characterization of cancer susceptibility regions in the human genome.
Chanock co-leads several international consortial studies to identify and characterize the genetics of cancer susceptibility including BRCA Challenge, Game-On, and the NCI Cohort Consortium.
His work focuses specifically on efforts to clarify the genetic architecture of cancer susceptibility,[2][3] the scope of genetic mosaicism and its contribution to cancer risk,[4][5] and how germline variation informs our understanding of somatic alterations in cancer[6][7] and investigation of how ionizing radiation causes thyroid cancer in children exposed to the Chornobyl accident and the lack of evidence for a transgenerational effect in cleanup workers following the Chornobyl accident.