His research portfolio while at DARPA included early funding of the MIT Architecture Machine Group now known as the MIT Media Lab, research in artificial intelligence at Yale University and Carnegie-Mellon University, computer simulation, computer-aided decision analysis and computer-based crisis management.
Andriole is also well known for the design and development of the United States' first totally online Masters program in information systems (MSIS), with the support of Alfred P. Sloan Foundation while at Drexel University.
He was also the principal architect of the investment strategy of Safeguard Scientifics, Inc. (NYSE: SFE) that led to multiple Initial Public Offerings (IPOs) of Internet companies with a total market capitalization of over $100B.
He is a Fellow of the Cutter Consortium, was a charter member of the U.S. government's Senior Executive Service (SES), received the Defense Meritorious Civilian Service Award for his work at DARPA, and was awarded an Honorary Doctorate from La Salle University in 2000.
IIS specialized in requirements analysis and prototyping, the design of user-computer interfaces, and software systems evaluation.
Andriole was a (tenured, full) Professor of Information Systems and Electrical & Computer Engineering at Drexel University in Philadelphia, Pennsylvania.
While at Drexel University, with support from the Alfred P. Sloan Foundation, he designed and implemented the nation's first totally online Masters program in information systems (MSIS).
The ISSE department was home to 30 professors and had an annual external sponsored research budget of over $5 million.