[27][28] In 2007, Jenner, along with her parents and siblings, Kendall, Kourtney, Kim, Khloé, and Rob, began appearing in the reality television series Keeping Up with the Kardashians, which chronicles the personal and professional lives of their family members.

[36] Later in 2012, she starred alongside her sister Kendall and mother Kris Jenner in an episode of American reality television series America's Next Top Model.

The Jenner sisters co-hosted the 2014 Much Music Video Awards, where Kylie made her acting debut in a promo for the show in Toronto, Ontario, Canada, in June 2014.

However, the Jenners' creative director, Elizabeth Killmond-Roman, clarified that the two had numerous Skype and FaceTime calls with Sloan to discuss the content of the novel.

The Jenner sisters were booed while introducing brother-in-law Kanye West's performance at the Billboard Music Awards in May 2015.

[50] Jenner released a three-minute-long promotional video for a series of lip glosses in March 2016, directed by Colin Tilley and starring fellow models Karin Jinsui, Mara Teigen, and Jasmine Sanders.

[61][62] In May 2016, she made her musical debut rapping on producer Burberry Perry's song "Beautiful Day", with Lil Yachty, Jordyn Woods, and Justine Skye.

[64] In April 2017, she made a surprise appearance at the Rio Americano High School prom in Sacramento alongside junior Albert Ochoa after hearing that his date had turned him down.

[73][74] The brand began producing dermis products, including face washes, scrubs, moisturizers and makeup removing wipes.

This marked their third collaboration after previously launched special collection of lip products called Koko Kollection in 2016 and the second part in 2017.

[75] In September, Jenner announced that she was serving as the makeup artistic director for Balmain's Spring 2020 runway show at Paris Fashion Week.

[80][81] The next month, Jenner sold a 51 percent stake in Kylie Cosmetics to Coty, which owns other beauty brands including Covergirl, OPI, Rimmel, GHD and Clairol for $600 million.

[85] Jenner made a cameo appearance in singers Ariana Grande and Justin Bieber's "Stuck with U" music video in May 2020.

The following month, the Jenners sisters addressed reports that their fashion brand Kendall + Kylie has failed to pay factory workers in Bangladesh as a result of the COVID-19 pandemic.

As a result, the Jenners stated that their company is owned by a separate entity known as 3072541 Canada Inc. even though they say that their brand "has worked with CAA-GBG in the past, in a sales and business development capacity only" and that they "do not currently have any relationship at all with GBG".

[89] In 2020, Jenner and her family announced that their reality show, Keeping Up With the Kardashians, would be ending after twenty seasons and almost 15 years on air.

[94] Following release, the company received a lot of backlash on social media, with people saying that the products were poor quality and impractical, saying that they should only be used for Instagram photos.

[98] In January 2022, Jenner became the first woman to gain 300 million followers on the social network service Instagram, surpassing the previous recordholder, singer Ariana Grande.

[100][101][102] The show features Jenner, alongside her sisters Kourtney, Kim, Khloe and Kendall, and mother Kris Jenner, it also features ex and current partners including Scott Disick, Travis Barker, Tristan Thompson, and Corey Gamble, with Kanye West making a guest appearance.

[114] She also launched a canned cocktail called Sprinter the same year which is available in the flavors black cherry, peach, grapefruit and lime.

[140] Their friendship ended in 2019 as a result of Woods cheating with Tristan Thompson, who was the fiancé of Jenner's half-sister Khloé Kardashian.

[147] Some discussions took a more serious tone, with journalists writing pieces on wealth distribution, inequality and inheritance, as well as upward mobility in society.

[154] Remake, a non-profit, labeled Global Brands Group as the manufacturer for the Kendall + Kylie clothing line.

Jenner later credited Vlada on social media and her work on the creation of the logo and an undisclosed settlement was paid to avoid any future legal issues.

[162] Sara Pope, a British painter whose work has been featured in art galleries in several cities across the globe, filed a lawsuit against Jenner and NBC Universal for the use of a neon lip logo.

[175] In June 2015, the Jenner sisters launched their clothing line Kendall + Kylie with British fashion retailer Topshop.

[187] Jenner set up an eBay account where she auctions old clothing to raise money for the Children's Hospital Los Angeles.

[189] The Jenner sisters participated in singer Chris Brown's two Kick'n It For Charity Celebrity Kickball games in Glendale, California on July 19, 2014[190] and on August 16, 2014.

[195] In September 2019, during her appearance on The Ellen DeGeneres Show, Jenner donated $750,000 to the founder and members of a feminist organization in Florida called Nest of Love, which is dedicated to mentoring young women, helping low-income kids in the community, and promoting female empowerment.

[197] In March 2020, Jenner, her mother Kris, along with beauty company Coty donated over 6,000 pounds of hand sanitizers to Southern California hospitals to help health care workers fighting the COVID-19 pandemic.