Straceburch was established in 1267 by Duke Barnim I of Pomerania at a strategically important site near the border with Mecklenburg in the west and the Margraviate of Brandenburg in the south.

The region was affected by the enduring Brandenburg–Pomeranian conflict, and after the Hohenzollern elector Frederick II of Brandenburg had campaigned the territory, the Pomeranian dukes finally were forced to cede Strasburg to him according to the 1479 Treaty of Prenzlau.

The town was a part of the Prussian Province of Brandenburg from the 19th century until in 1952 the East German government established the Bezirk Neubrandenburg comprising the former Brandenburg towns of Prenzlau, Templin and Strasburg.

Strasburg then was the capital of a district in its own right, which after the East German Peaceful Revolution of 1989 became part of the state of Mecklenburg-Vorpommern.

Strasburg, Germany is twinned with: This Vorpommern-Greifswald location article is a stub.