Streptazolin

Streptazolin is an antibiotic and antifungal substance isolated in 1981 from Streptomyces viridochromogenes.

[2][3] Because of its polymerisation tendency, it is not suitable for therapeutic use.

1,4-reduction of the conjugated diene gives dihydrostreptazolin which is stable, but has very limited antimicrobial properties.

[2] The first total synthesis of (racemic) streptazolin was achieved in 1985 with the aid of a modified Ferrier rearrangement.

This antiinfective drug article is a stub.

(+)-Dihydrostreptazolin