As with all compounds of strontium, this salt emits a bright red colour in flame, and is commonly used in fireworks to that effect.

SrCl2 is useful in reducing tooth sensitivity by forming a barrier over microscopic tubules in the dentin containing nerve endings that have become exposed by gum recession.

Known in the U.S. as Elecol and Sensodyne, these products are called "strontium chloride toothpastes", although most now use saltpeter (KNO3) instead which works as an analgesic rather than a barrier.

A commercial company is using a strontium chloride-based artificial solid called AdAmmine as a means to store ammonia at low pressure, mainly for use in NOx emission reduction on Diesel vehicles.

Strontium chloride is used with citric acid in soil testing as a universal extractant of plant nutrients.