The Study of Transition, Outcomes, and Gender (STRONG) is a cohort study of health in transgender people before and during or after gender-affirming treatments such as gender-affirming hormone therapy and gender-affirming surgery.
[1] It is being conducted at Kaiser Permanente sites in Northern California, Southern California, and Georgia and includes over 6,000 transgender people.
[1] The study was underway by 2015[2] and the first paper for the study was published in 2017.
[1] The STRONG cohort represents the largest cohort of transgender people studied to date and the first such large-scale study conducted in the United States.
[2] STRONG has published papers assessing transgender population size and demographics,[3] agreement between electronic medical records and self-reported gender identity,[4] gender dysphoria and mental health,[5][6] suicidality,[7] "passing" and mental health,[8] progression of gender dysphoria in transgender youth,[9] hematological parameters,[10] liver parameters,[11] acne risk,[12][13] psoriasis risk,[14] cardiovascular health,[15][16] diabetes risk,[17][18] and cancer risk.