Styx Creek is a small to medium-sized natural stream in the Central Otago region of New Zealand.

Originally the second overnighting stop from Dunedin (after Clark's Junction), its importance meant two hotels operated on either side of the river in case there was a flood.

This settlement situated on an outcrop of flat land originally bordered on three sides by the river, and on the fourth by a sheer cliff face and the surrounding area became known as "The Styx".

When gold was discovered in Central Otago the provincial government was quick to take over the responsibility of moving the precious metal safely to Dunedin.

[2] As a result, a stone stable was built in the 1860s to cater for the horses of the gold escort and other travellers, while they stayed at the Styx Hotel which was located next door.