From his childhood, he rebelled against his family, against the Upanishad text Bhagavat-Bhajana, against the Sanatan system, against current literature and painting.
He left Tagore family at the age of twenty-six with a share of his ancestral property.
Nirode Mazumdar formed the Calcutta Group in 1943 with young artists such as Pradosh Dasgupta, Gopal Ghose, Paritosh Sen, Kamala Das Gupta, Rathin Maitra, Pranakrishna Pal etc., moving away from the art thinking of the Bengal School.
Four-five issues of the Chaturanga magazine were published under his editorship while studying in art college.
During thirties, he edited the monthly magazine Bhavishyat (The Future) and the pictorial weekly Agragati (The Progress) with his own style of adventurous writing, pictures, designs and decorations that were novel and startling.
Unloved, neglected objects, pictures, statues, pots, antique furniture, lanterns, prayer pens, rare ink pots, Mughal hookah cigarettes, cigar pipes, old maps, letters of sages — he was rich in such strange collections.