The Succulent Karoo is an ecoregion defined by the World Wide Fund for Nature to include regions of desert in South Africa and Namibia,[2] and a biodiversity hotspot.

The Succulent Karoo stretches along the coastal strip of southwestern Namibia and South Africa's Northern Cape Province, where the cold Benguela Current offshore creates frequent fogs.

The ecoregion extends inland into the uplands of South Africa's Western Cape Province.

It is bounded on the south by the Mediterranean climate fynbos, on the east by the Nama Karoo, which has more extreme temperatures and variable rainfall, and on the north by the Namib Desert.

Monkey beetles, largely endemic to southern Africa, are concentrated in the Succulent Karoo and are important pollinators of the flora.