It is the second Super Robot Taisen game that was officially released in North America.

The story selection system of Super Robot Taisen: Original Generation has been removed, replacing it with a branching storyline during certain intervals of the game.

In addition, a total of four new series (three of them past Super Robot Wars games, while one is a manga) appear, adding new characters, mechs, major events from the respective stories of the series and some original creations for this game itself.

Seeing a greater need to defend the Earth from future extraterrestrial invaders, the Earth Federation Army begins to mass-produce its line of Personal Troopers, as well as introducing new mechs to combat alien threats to humanity, after the Tokyo Manifest announcement.

Meanwhile, behind the shadows, mysterious beings are at work, eagerly awaiting their chance to strike and subjugate humanity, or perhaps destroy it, as even greater forces, more powerful and menacing than the Aerogaters, begin to slowly appear...