During the formation of the brand, Jebbia was inspired by a book on Barbara Kruger's artwork, which influenced the design of Supreme's red box logo with white Futura Heavy Oblique font.

The store's first employees included skaters and actors, such as Justin Pierce and Harold Hunter,[6] as well as extras from the Larry Clark film Kids.

[10] In 2004, a second location was opened on North Fairfax Ave. in Los Angeles, California, nearly double the size of the original New York City store.

McSweeney secured the services of a civil rights attorney and legal heavyweight Norman Siegel to represent her in court.

[15] On October 6, 2017, Jebbia confirmed that the label had sold roughly 50% of the stake in the company to private equity firm The Carlyle Group for around $500 million.

[21] Supreme's skate team has included Aidan Mackey, Brian Anderson, Ben Kadow, Jason Dill, Sean Pablo, Tyshawn Jones, Mark Gonzales, Kader Sylla, Sage Elsesser, Rowan Zorilla, Seven Strong, Troy Gipson, Vince Touzery, Caleb Barnett, Yuto Horigome, Nik Stain, Kevin Rodrigues, and Beatrice Domond.

[21][9] Following the Paris store's opening in 2016, Supreme also formed a French skate team that includes Dayanne Akadiri, Manuel Schenck, Lucien Momy, Dadoum Chabane, Damien Bulle, Victor Demonte, Valentin Jutant, and Samir Krim.

[31] In November 2019, an appellate court of the European Union Intellectual Property Office (EUIPO) recognized the distinctiveness of Supreme's brand, making it eligible for an EU trademark.

This includes Michael Jordan, Kermit the Frog,[36] Three 6 Mafia, Lou Reed, Lady Gaga, Neil Young,[37] Gucci Mane, Nas, and Morrissey.

William "Bill" Strobeck serves as Supreme's main filmmaker and has produced several web edits for the brand, such as Joyride (2014),[38] Swoosh (2015),[39] and King Puppy (2016).

A subsequent collaboration in 2022 emphasized the same trend, with the Blitzkrieg collection incorporating graphics and designs from the Tekken video game series.