She began a lifelong friendship with fellow artist Annie Swynnerton; the two women pursued their art studies in Rome and Paris between 1874 and 1880.
[3] Around 1872, Lord Leighton dictated notes and observations on his methods of painting and composing his pictures to Isabel Dacre, during a stay on the island of Capri.
From 1877–80 she was in Paris at the Académie Julian with a fellow - pupil Marie Bashkirtseff and bracketed with her as first in the concourse mentioned in the famous diary.
Dacre was associated with Julian's atelier on two occasions: 1878–79 when she completed a striking black and white chalk drawing, Portrait of a Young Girl in a Satin Cap, ca.
After living in London for a time she returned to Manchester in 1883 and shared a studio in 10 King Street with the artist Mary Florence Monkhouse.