Powers began painting in 1979, encouraged by a friend and fellow painter who had seen her expressive pencil drawings.
Only a year later, her work had been accepted for display by the prestigious Jay Johnson Folk Heritage Gallery in New York City.
The folk art still lifes of Susan Powers have been compared with the trompe-l'œil works of the well-known 19th-century American academic artist William Harnett.
Her paintings are in many permanent collections, including the Smithsonian Institution in Washington, D.C., and the American Museum in Bath, England.
Her works have been exhibited in numerous museums, including the Bede Gallery, Jarrow, England, the Woodspring Museum, Weston-super-Mare, England, the Camden Arts Center, London, the Haworth Art Gallery, London, and at the White House in Washington, D.C. ” The still lifes of Susan Powers have been compared with the trompe-l'œil works of the well-known 19th–century American academic artist William Harnett.