Susan Joan Wetzel Pope (born September 10, 1942 in Summit) is an American politician from Wayland, Massachusetts.

In 1996, Pope first ran for office in the Republican primary election for the Massachusetts House of Representatives' 13th Middlesex district against Maryann K. Clark.

Pope won and was also victorious in the general election against Russell A. Ashton of the Democratic Party, succeeding Nancy Hasty Evans, another female Republican from Wayland.

She continued to hold the post until defeat by Tom Conroy in the Massachusetts House of Representatives election in 2006.

Pope was a member of the The Wish List, a political action committee dedicated to electing pro-abortion rights Republican women into office.