Heerfordt, who was originally from Hungary, had been running the pharmacies in Nykøbing Falster and Nakskov for a couple of years but they were now passed on to two of his sons-in-law.

He died in 1691 and the pharmacy was then run by his widow Cecilie Iversdatter until 1721 and it stayed in the family until 31 December 1782.

Johann Andreas Mühlensteth purchased the pharmacy in 1781 and was at the same time granted permission to move it to a site in Østergade.

In August 1825 the pharmacy changed hands again when it was acquired by Therkel Johannes Gottlob Schønberg Baagoe.

His widow Hedvig Harlotte, née Andresen, continued the operations after his death in 1837.

It was designed by the architect Bent Helweg-Møller in collaboration with the engineers C. N. Nøkkentved and Svend Friis Jespersen.