After playing supporting roles, she made her debut as a lead actress in the Tamil film Subramaniapuram (2008).

Swathi Reddy was born in Vladivostok, located in the southerly reaches of the Russian Far East in the erstwhile Soviet Union.

Reddy's family moved to Mumbai and later to the Eastern Naval Command, Visakhapatnam, where she spent most of her childhood.

[5] After the completion of her first year of graduation, she got an offer to make her film debut in Krishna Vamsi's Danger (2005).

Priyanka Pulla of fullhyd.com wrote, "Swati making her much-anticipated debut here, has a role somewhat akin to a single member in a Mexican wave - contributory, but not self-sufficient enough to be judged.

In 2010, she gave her voice to an HIV/AIDS education animated software tutorial created by the nonprofit organization TeachAids.